crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 196270

Časopis

Autori: Pavelić, Krešimir; Slijepčević, Milivoj; Pavelić, Jasminka; Ivić, Jasna; Jurković-Audy, Silvana; Pavelić, Zlatko; Boranić, Milivoj
Naslov: Growth and treatment of Ehrlich tumor in mice with alloxan-induced diabetes
Izvornik: Cancer research (Baltimore) (0008-5472) 39 (1979), 5; 1807-1813
Vrsta rada: članak
Ključne riječi: Ehrlich tumor ; mice ; alloxan ; diabetes
Sažetak:
Hypoglycemia and hypoinsulinemia accompanied i.p. or i.m. growth of the Ehrlich tumor in CBA/H and BALB/c mice. Simultaneously, insulin accumulated in the ascitic fluid of tumor-bearing mice. In hosts rendered diabetic by means of alloxan, the tumor decreased the blood glucose almost to the level seen in nondiabetic mice. Tumor growth was retarded in diabetic hosts, but cells from such tumors, transplanted into secondary diabetic recipients, grew faster than in their primary diabetic hosts, similarly to “nondiabetic” tumor cells growing in nondiabetic hosts. This phenomenon of “adaptation” of the tumor to the diabetic state was prevented if diabetic tumor-bearing mice were daily treated with insulin. The tumor did not grow in all diabetic recipients ; the frequency of takes correlated with severity of the diabetes, i.e., with the dose of alloxan given to induce it. The greater the dose, the less mice accepted the tumor. Insulin injection into diabetic tumor-bearing mice promoted the tumor growth. Simultaneous treatment of diabetes and the tumor afforded the best antitumor effect.
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL Internet adrese: http://cancerres.aacrjournals.org/content/canres/39/5/1807.full.pdf
http://cancerres.aacrjournals.org/content/39/5/1807.short
URL cjelovitog teksta:
Google Scholar: Growth and treatment of Ehrlich tumor in mice with alloxan-induced diabetes



  Verzija za printanje   za tiskati


upomoc
foot_4