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Pregled bibliografske jedinice broj: 197131

Časopis

Autori: Slade, Neda; Levanat, Sonja; Spaventi, Šime; Pavelić, Krešimir
Naslov: Collagenase derived from human fibrosarcoma is responsible for degradation of basement membranes
Izvornik: International journal of experimental pathology (0959-9673) 72 (1991), 6; 715-724
Vrsta rada: članak
Ključne riječi: human fibrosarcoma ; collagenase ; invasion
Sažetak:
A collagenase-like enzyme with the ability to degrade the proteins of artificial basement membranes (BM) was isolated from human fibrosarcoma. Secretion of the same peptide was observed from the primary fibrosarcoma cell cultures. This peptide degrades the artificial basement membranes derived from bovine corneal endothelial cells. Using electrophoretic methods it was found that the isolated and partially purified enzyme consists of eight bands of different molecular mass corresponding to the collagenase standard from Cl. histolyticum. Only two bands with molecular masses of 22 000 (pI 5.5) and 63 000 (pI 5.9) degrade BM.
Izvorni jezik: ENG
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bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL Internet adrese: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002443/
URL cjelovitog teksta:
Google Scholar: Collagenase derived from human fibrosarcoma is responsible for degradation of basement membranes



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