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 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 197366

Časopis

Autori: Vuk-Pavlović, Zvezdana; Pavelić, Krešimir; Vuk-Pavlović, Stanimir
Naslov: Modulation of in vitro growth of murine myeloid leukemia by an autologous substance immunochemically cross-reactive with insulin and antiinsulin serum
Izvornik: Blood (0006-4971) 67 (1986), 4; 1031-1035
Vrsta rada: članak
Ključne riječi: in vitro ; murine myeloid leukemia ; immunochemically ; cross-reactive ; antiinsulin serum
Sažetak:
Murine myeloid leukemia secretes a substance immunochemically cross- reactive with insulin (SICRI) both in vivo and in serum-free media. High SICRI concentrations in peripheral blood of tumorous animals do not affect circulating glucose levels. In culture, DNA synthesis rate per leukemic cell is proportional to cell density and is reduced by antiinsulin serum. Culture medium conditioned by leukemia cells as well as SICRI affinity purified from this medium stimulate DNA synthesis in cultured leukemia cells. It appears that autocrine stimulation of murine myeloid leukemia can be mediated in part by an insulin-related growth factor.
Izvorni jezik: ENG
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bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL Internet adrese: http://www.bloodjournal.org/content/67/4/1031.full.pdf
http://www.bloodjournal.org/content/67/4/1031
URL cjelovitog teksta:
Google Scholar: Modulation of in vitro growth of murine myeloid leukemia by an autologous substance immunochemically cross-reactive with insulin and antiinsulin serum



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