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 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 2225

Časopis

Autori: Popović Hadžija, Marijana; Poljak-Blaži, Marija; Pavelić, Krešimir
Naslov: Presence of c-myc protein in murine myeloid leukaemia cells during growth and after irradiation
Izvornik: Anticancer research (0250-7005) 17 (1997), 2A; 1089-1092
Vrsta rada: članak
Ključne riječi: myeloid leukaemia; mice; proto-oncogene; c-myc
Sažetak:
Myeloid leukaemia (ML) is strain specific for RFM mice, which were used in these experiments. We investigated the presence of c-myc protein during the growth of ML and after irradiation of leukaemic cells. Leukaemic spleen cells were investigated 9 (nonterminal phase NTP) or 12 days (terminal phase TP) after the injection of ML cells. Leukaemic cells of NTP were irradiated with X-rays or UV-light. c-Myc protein was detected by immunocytochemical method. c-Myc protein was expressed in 74.98% of spleen cells of healthy RFM mice. In the early period of leukaemia growth (NTP) only 14.33% of c-myc positive cells were found as opposed to the terminal phase (TP) of leukaemia when 89.7% of c-myc positive cells were detected. These results indicated the connection of growth of ML and the presence of c-myc protein. If the spleen cells of NTP of leukaemia were irradiated by X-rays or UV-light, the number of cells which expressed c-myc protein was extremely increased. [References: 21]
Projekt / tema: 00981104, 00981109
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL cjelovitog teksta:
Google Scholar: Presence of c-myc protein in murine myeloid leukaemia cells during growth and after irradiation



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