engleski

Liposomes with metronidazole for topical use: the choice of preparation method and vehicle

Liposomes containing metronidazole were prepared for the treatment of skin disorder Rosacea. To optimize the composition and size of liposomes, natural and synthetic lipidswere used in three different preparation methods. Optimal liposomal preparation was incorporated into five dermal vehicles (three O/W emulsion creams and two gels) and vehicles tested for the stability (at 20 and 40 degree) during a storage period of 4 weeks.

liposomes; metronidazol; topical application

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