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Patterns of neurocognitive dysfunction and personality traits in families with schizophrenia (CROSBI ID 518305)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Jablensky, Assen ; Dragović, Milan ; Badcock, C. Johanna ; Cloninger, Robert Patterns of neurocognitive dysfunction and personality traits in families with schizophrenia. 2005

Podaci o odgovornosti

Jablensky, Assen ; Dragović, Milan ; Badcock, C. Johanna ; Cloninger, Robert

engleski

Patterns of neurocognitive dysfunction and personality traits in families with schizophrenia

Two homogeneous schizophrenia subtypes, each featuring a specific configuration of neurocognitive performance, neurobehavioural anomalies and selected personality measures, were identified in our previous study. The first, “ Cognitive Deficit” (CD) type, comprising patients and a small number of unaffected relatives (n = 76), displayed pervasive deficit on almost all neurocognitive measures. Family members assigned to the remaining types (n = 312) were close to controls on neurocognitive measures but showed significantly deviant scores on temperament and character scales and three dimensions of schizotypy, and were pooled into Non-CD type. We examined whether specific profiles of personality were related to schizotypal dimensions and, once the relationship was confirmed, whether such a link was invariant across both groups. Additionally, this link was also investigated in a sample of healthy community controls (n = 143). Simple mean scores on personality scales and schizotypy factors were generally uninformative, with relatives of schizophrenia patients having virtually identical scores on almost all scales as control subjects. However, distinct associations between structure of personality traits (temperament and character) and schizotypal factors emerged in the two schizophrenia subtypes. Whereas reduced cognitive efficiency in CD patients was primarily reflected in negative symptomatology, dysfunctional cognitive control could be responsible for more prominent positive symptoms in Non-CD patients, their clinically unaffected relatives, and controls.

schizophrenia; schizotypal personality; temperament and character; canonical analysis

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Podaci o prilogu

2005.

objavljeno

Podaci o matičnoj publikaciji

Podaci o skupu

The 8th World Congress of Biological Psychiatry

predavanje

01.01.2005-01.01.2005

Beč, Austrija

Povezanost rada





Kliničke medicinske znanosti, Psihologija