engleski

Atypical self-reported handedness and hand performance in schizophrenic patients and their first-degree relatives

This paper investigates prevalence of atypical lateralisation of hand preferences in schizophrenia patients and their asymptomatic first-degree relatives. The presence of mixed- (OR=3.766 ; 95%CI=1.93-7.35 ; p<0.000) and non-right-handedness (OR=3.997 ; 95%CI=2.19-7.29 ; p<0.000) in schizophrenic patients was higher than in control subjects, when the preference inventory (Oldfield) was used as a measure of handedness. Mixed-handedness was more characteristic for male patients than females, but without statistical significance. There was no trend of increased mixed- and non-right-handedness in the group of relatives compared to control subjects. Aberrant handedness lateralisation of itself, specifically the mixed-handedness, in schizophrenic patients was not associated with impaired cognitive performance on the array of various domains. An intriguing interaction effect was found in the group of patients, linking mixed-handedness with markedly impaired sustained attention, but only in males.

schizophrenia; hand perferences; hand performance; laterality

nije evidentirano