Hrvatska znanstvena bibliografija (CROSBI)



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Zbornik radova

Autori: Čikeš Čulić, Vedrana; Kurir Tičinović, Tina; Radić, S.; Zemunik, Tatijana; Mesarić, M.; Markotić, Anita
Naslov: Exposure to hyperbaric pressure alters ganglioside expression in rat liver following partial hepatectomy
( Exposure to hyperbaric pressure alters ganglioside expression in rat liver following partial hepatectomy )
Izvornik: Abstracts of the 31st FEBS Congress "Molecules in Health and Disease" ; u: The FEBS Journal 273 (2006) (S1) ; PP-691 / Perham, Richard (ur.). - Oxford : Blackwell Publishing Ltd , 2006. 264-264.
ISSN: 1742-464X
Skup: 31st FEBS Congress "Molecules in Health and Disease"
Mjesto i datum: Istanbul, Turska, 24.-29.06.2006.
Ključne riječi: hyperbaric oxygenation; liver regeneration; gangliosides
( hyperbaric oxygenation; liver regeneration; gangliosides )
Sažetak:
Remnant liver after partial hepatectomy (PH) demands an increased amount of oxygen to restore hepatic energy. Modulation of the ganglioside content of hepatocyte plasma membrane could provide a mean for upregulating cellular responsiveness to a variety of factors. Rat liver gangliosides were analysed by high performance thin layer chromatography (HPTLC) followed with immunostaining 54 h after PH. Non-operated and three different groups of operated rats were studied according to the hausing conditions before or after operation: recovering under normal ambient conditions after operation (1), treating with hyperbaric pressure before operation and recovering under normal ambient conditions (2 or preHB), and recovering under hyperbaric pressure after operation (3 or postHB). Liver of preHB group showed the highest expression of ganglioside GD1a, a marker of a peculiar transition phase of liver regeneration. Same animals showed enhanced expression of the several gangliosides: GM2, GM1a, GD1b, GT1b, Gal-NAcGM1b, nLc4, nLc6 and nLc8. Since galactosyl- and N-acetylgalactosaminyltransferase catalyse final step of synthesis of GM2, GM1a, GD1b, Gal-NAcGM1b, nLc4, nLc6, and nLc8, our results point at possible role of galactosyl- and N-acetylgalactosaminyltransferase in regulation of the liver growth after PH.
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Međunarodna recenzija
Projekt / tema: 0216013
Izvorni jezik: eng
Kategorija: Znanstveni
Znanstvena područja:
Kemija,Temeljne medicinske znanosti
URL Internet adrese: http://www3.interscience.wiley.com/cgi-bin