crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 331106

Zbornik radova

Autori: Rozgaj, Ružica; Kašuba, Vilena; Milić, Mirta; Pizent, Alica; Kljaković-Gašpić, Zorana
Naslov: DNA damage in lymphocytes of lead workers determined by the alkaline comet assay
( DNA damage in lymphocytes of lead workers determined by the alkaline comet assay )
Izvornik: Abstracts of the 44th Congress of the European Societies of Toxicology / Dekant, Wolfgang (ur.). - Amsterdam : Elsevier , 2007. S116-S116.
ISSN: 0378-4274
Skup: The 44th Congress of the European Societies of Toxicology
Mjesto i datum: Amsterdam, Nizozemska, 07-10.10.2007.
Ključne riječi: DNA damage; lead workers; alkaline comet assay
( DNA damage; lead workers; alkaline comet assay )
Sažetak:
Lead and lead compounds are important pollutants in human living and working environment. Numerous studies have shown that lead adversely affects the nervous, haematopoietic, renal, endocrine and reproductive systems. The genotoxic effects of lead have been studied both in vivo and in vitro, but the published results are inconsistent. The aim of our study was to investigate the level of exposure to lead and its genotoxic effects in lymphocytes of occupationally exposed subjects. The study group consisted of 35 lead workers, 21 men and 14 women, and 35 control subjects matching in age, sex and the smoking habit. Blood lead concentrations were analysed using electrothermal atomic absorption spectrometry. The comet assay was used to evaluate the primary DNA damage. Mean blood lead level in the exposed group was ten times as high as in controls (344 µ ; g/l vs. 36 µ ; g/l), but the mean tail length (TL) and tail moment (TM) did not differ between the studied groups (15.12 vs. 15.48 and 0.28 vs. 0.33, respectively). However, significantly higher values of TL and TM were observed in some individuals in the exposed group. Although men had significantly higher blood lead concentrations, women with significantly higher TL and TM values showed to be more susceptible to lead exposure.
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Međunarodna recenzija
Projekt / tema: 022-0222411-2408, 022-0222148-2137
Izvorni jezik: eng
Kategorija: Znanstveni
Znanstvena područja:
Biologija
Upisao u CROSBI: vkasuba@imi.hr (vkasuba@imi.hr), 25. Tra. 2008. u 10:30 sati
Napomene:
Toxicology Letters (2007) (S) (1-240) ; ISSN 0378-4274 ; doi:10.1016/j.toxlet.2007.05.324



  Verzija za printanje   za tiskati


upomoc
foot_4