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Pregled bibliografske jedinice broj: 335871

Časopis

Autori: Ratkaj, Ivana; Štajduhar, Emil; Vučinić, Srđan; Spaventi, Šime; Pavelić, Krešimir; Bošnjak, Hrvojka; Kraljević Pavelić, Sandra
Naslov: Integrated gene networks in breast cancer development
Izvornik: Functional & integrative genomics (1438-793X) 10 (2010), 1; 11-19
Vrsta rada: pregledni rad
Ključne riječi: breast cancer ; metastasis ; functional genomics
Sažetak:
Breast cancer is a complex and heterogenous disease. Classical molecular medical approaches cannot fully understand and comprehend its pathogenesis. In this review, the development of new biological markers for the early detection and creation of guided and specific therapy of breast cancer are discussed in light of the rapid advances in the "omics". Results of cancer research in combination with large-scale methods that examine the expression status of genes and proteins have identified a large number of new biomarkers as well as confirmed the human growth hormone as an important player in the pathogenesis of this disease through its autocrine regulation where it influences the activation of Pax5 and HOXA1 gene networks.
Projekt / tema: 335-0000000-3532, 335-0982464-2393, 101-0982464-2277
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL Internet adrese: http://www.springerlink.com/content/08121612t7426425/?p=617c40b8f1724626a4ea52137a7c0640&pi=1
http://www.springerlink.com/content/08121612t7426425/fulltext.pdf
Broj citata:
Altmetric:
DOI: 10.1007/s10142-010-0159-2
URL cjelovitog teksta:
Google Scholar: Integrated gene networks in breast cancer development
Upisao u CROSBI: pavelic@irb.hr (pavelic@irb.hr), 2. Svi. 2008. u 19:45 sati



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