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Pregled bibliografske jedinice broj: 341958

Zbornik radova

Autori: Juretić, Davor; Bonačić-Lošić Željana; Županović, Paško; Dewar, Roderick
Naslov: Optimization of enzymatic kinetics by using MaxENT and MEP entropy principles
Izvornik: The 1st Split Meeting on Development and Applications of Novel Methods and Models in Computational Biophysics and Structural Bioinformatics
Skup: The 1st Split Meeting on Development and Applications of Novel Methods and Models in Computational Biophysics and Structural Bioinformatics
Mjesto i datum: Split, Hrvatska, 19-21.12.2007.
Ključne riječi: entropy production; information entropy; enzyme kinetics
Sažetak:
The question connecting physics and biology, which has never been resolved in the literature, is about interdependence of biological and thermodynamic evolution: are biological macromolecules and living cells optimized to produce as little or as much entropy as possible. Related question is about Shannon’ s (information) entropy: are present-day enzymes designed by evolution to have minimal or maximal information entropy. These questions will be discussed for steady state enzyme kinetics applied in modeling bacterial photosynthesis, the molecular motor of ATP synthase and generalized Michaelis-Menten mechanism for enzymatic reactions. We shall examine the hypothesis that natural evolution in biology can be predicted as well as evolution in thermodynamics by using the same rules of statistical mechanics, when assumption is made that the most probable behavior in each case is selected by the principle of maximum Shannon entropy and one of its corollaries – Maximum Entropy Production Principle.
Vrsta sudjelovanja: Pozvano
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Međunarodna recenzija
Projekt / tema: 177-1770495-0476
Izvorni jezik: ENG
Kategorija: Ostalo
Znanstvena područja:
Fizika,Biologija
Upisao u CROSBI: juretic@pmfst.hr (juretic@pmfst.hr), 7. Svi. 2008. u 12:24 sati
Napomene:
Conference program and abstracts of invited talks for the meeting: The 1st Split Meeting on Development and Applications of Novel Methods and Models in Computational Biophysics and Structural Bioinformatics are available at the: http://www.pmfst.hr/se/z_fizika/konf/



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