Madelung’ s disease: case report and review of the literature (CROSBI ID 140845)
Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija
Podaci o odgovornosti
Bulum, Tomislav ; Duvnjak, Lea ; Car, Nikica ; Metelko, Željko
engleski
Madelung’ s disease: case report and review of the literature
Madelung’ s disease is an extremely rare disorder of unknown etiology, characterized by prominent, symmetric masses of adipose tissue on the neck, shoulders, arms and upper parts of the trunk. Although benign in its nature, tongue or mediastinal involvement can cause compression syndromes of the trachea and superior vena cava leading to dyspnea, dysphagia and dysphonia. It predominantly affects men between the ages of 30 and 60 years, of Mediterranean origin and with a history of alcohol abuse. The disorder can also be associated with hyperlipoproteinemia, hyperuricemia, diabetes mellitus and hypothyroidism. The only effective treatment is surgical removal or liposuction, but recurrences are common. A case of a 51-year-old man with unusual pseudoathletic appearance, history of excessive alcohol consumption and subcutaneous fat tissue biopsy is presented and typical features of Madelung’ s disease are discussed.
Madelung’ s disease; benign symmetric lipomatosis; lipomas; alcoholism
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