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Pregled bibliografske jedinice broj: 346899

Zbornik radova

Autori: Marjanović, Damir; Durmic-Pasic, Adaleta; Pjanic, N; Bakal, Narcisa; Kovačević, Lejla; Škaro, Vedrana; Projić, Petar; Haverić, Sanin; Bajrović, Kasim; Hadžiselimović, Rifat; Primorac, Dragan; Pojskić Naris
Naslov: Population study at fifteen short tandem repeat loci in the representative sample of Bosnia and Herzegovina residents - contemporary data
Izvornik: European Journal of Human GeneticsNature Publishing Group , 2007. 305-305.
ISSN: 1018-4813
Skup: European Human Genetics Conference
Mjesto i datum: Nica, Francuska, 16-19. 06. 2007.
Ključne riječi: STR loci; renewed data; Bosnia & Herzegovina
Sažetak:
In our previous population studies of B&H human population, we used 17 autosomal and 12 Y-chromosomal STR loci, as well as 28 NRY bi-allelic markers to generate referent database. Wishing to test our database in order to obtain specific results in various DNA analysis, we have decided to analysis additional individuals, firstly at fifteen autosomal STR loci (D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, vWA, D8S1179, TPOX, FGA). Therefore, we have tested additional group of 100 unrelated healthy individuals born in B&H. Qiagen DnaeasyTM Tissue Kit was used for DNA extraction from buccal swabs and bloodstains and PowerPlex 16® ; ; System for amplification and detection. The total volume of PCR reaction was 5μ l and PCR amplifications were carried out in PE GeneAmp PCR System Thermal Cycler. Electrophoresis of the amplification products was preformed on an ABI PRISM 310 genetic analyzer. The raw data were compiled and analyzed using Genemapper® ; ; v3.2. Deviation from Hardy-Weinberg equilibrium, observed and expected heterozygosity, power of discrimination and power of exclusion were calculated. Statistical differences between the new set of data and the data at same loci published earlier (based on 100 tested individuals) indicated the advantage of using recently obtained frequencies, especially as it pertains to the forensic-genetic statistical analysis. In addition, we compared B&H data with the data obtained from geographically closer European populations. The results of this study will be used as guidelines in additional improving of investigation of recent B&H human populations, initiated in our previous studies.
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Međunarodna recenzija
Projekt / tema: 309-1300855-2738
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Biologija
Upisao u CROSBI: vskaro@irb.hr (vskaro@irb.hr), 9. Svi. 2008. u 12:47 sati



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