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Pregled bibliografske jedinice broj: 357150

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Autori: Telišman, Spomenka; Pizent, Alica; Prpić-Majić, Danica
Naslov: Lead interference in zinc metabolism and the lead and zinc interaction in humans as a possible explanation of apparent individual susceptibility to lead
( Lead interference in zinc metabolism and the lead and zinc interaction in humans as a possible explanation of apparent individual susceptibility to lead )
Izvornik: Heavy Metals in the Environment / Allan RJ, Nriagu JO (ur.). - Edinburgh : CEP Consultants , 1993. 404-407 (ISBN: 0 905941 51 9).
Skup: 9th International Conference on Heavy Metals in the Environment
Mjesto i datum: Toronto, Kanada, 12.-16.09.1993.
Ključne riječi: blood lead; serum zinc; seminal zinc
( blood lead; serum zinc; seminal zinc )
Sažetak:
Serum zinc (ZnS), seminal fluid zinc (ZnF), blood lead (PbB), and activity of erythrocyte delta-aminolevulinic acid dehydratase (ALAD) were measured in 152 adult male subjects, not occupationally exposed to zinc: 101 lead workers with long-term slight to moderate occupational lead exposure and 51 control subjects with no occupational lead exposure. Significant correlations were found between a decrease of ZnS with respect to an increase of PbB (r=-0.135, P<0.05) and a decrease of ALAD (r=0.237, P<0.002), between a decrease of ZnF with respect to PbB (r=-0.245, P<0.001) and ALAD (r=0.262, P<0.001), and between ZnS and ZnF (r=0.255, P<0.001). The results indicate possible lead interference in zinc metabolism resulting in relative zinc deficiency, and thus lead-zinc interaction which can influence ALAD as well as some other lead-related effects. This might explain a large part of the interindividual differences in response to the same PbB level, i.e. apparent individual susceptibility to lead, which was ascribed to genetic factors.
Vrsta sudjelovanja: Predavanje
Vrsta prezentacije u zborniku: Cjeloviti rad (više od 1500 riječi)
Vrsta recenzije: Međunarodna recenzija
Izvorni jezik: eng
Kategorija: Znanstveni
Znanstvena područja:
Javno zdravstvo i zdravstvena zaštita
Upisao u CROSBI: apizent@imi.hr (apizent@imi.hr), 28. Svi. 2008. u 17:38 sati



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