Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi

Biomedical Potentials of Crown Ethers: Prospective Antitumor Agents (CROSBI ID 145020)

Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija

Kralj, Marijeta ; Tušek-Božić, Ljerka ; Frkanec, Leo Biomedical Potentials of Crown Ethers: Prospective Antitumor Agents // ChemMedChem, 3 (2008), 10; 1478-1492. doi: 10.1002/cmdc.200800118

Podaci o odgovornosti

Kralj, Marijeta ; Tušek-Božić, Ljerka ; Frkanec, Leo

engleski

Biomedical Potentials of Crown Ethers: Prospective Antitumor Agents

Crown ethers are of enormous interest and importance in chemistry, biochemistry, materials science, catalysis, separation, transport and encapsulated processes, as well as in the design and synthesis of various synthetic systems with specific properties, diverse capabilities, and programmable functions. Classical crown ethers are macrocyclic polyethers that contain 3– 20 oxygen atoms separated from each other by two or more carbon atoms. They are exceptionally versatile in selectively binding a range of metal ions and a variety of organic neutral and ionic species. Crown ethers are currently being studied and used in a variety of applications beyond their traditional place in chemistry. This review presents additional applications and the ever-increasing biomedical potentials of these intriguing compounds, with particular emphasis on the prospects of their relevance as anticancer agents. We believe that further research in this direction should be encouraged, as crown compounds could either induce toxicities that are different from those of conventional antitumor drugs, or complement drugs in current use, thereby providing a valuable adjunct to therapy.

antitumor agents ; biological activity ; crown compounds ; ion channels ; ionophores

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o izdanju

3 (10)

2008.

1478-1492

objavljeno

1860-7179

1860-7187

10.1002/cmdc.200800118

Povezanost rada

Kemija, Biologija, Temeljne medicinske znanosti

Poveznice
Indeksiranost