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 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 381240

Časopis

Autori: Sredoja Tišma, Vesna; Basta-Juzbašić, Aleksandra; Jaganjac, Morana; Brčić, Luka; Dobrić, Ivan; Lipozenčić, Jasna; Tatzber, Franz; Žarković, Neven; Poljak-Blaži, Marija
Naslov: Oxidative stress and ferritin expression in the skin of rosacea patients
Izvornik: Journal of American Academy of Dermatology (0190-9622) 60 (2009), 2; 270-276
Vrsta rada: članak
Ključne riječi: rosacea; oxidative stress; ferritin; peroxide; antioxidants
Sažetak:
Rosacea is a common chronic inflammatory skin disease of unknown etiology. Because it is evident that rosacea is a light - sensitive skin disease, the purpose of this work was to determine the parameters of oxidative stress, anti-oxidative capacity and the pathophysiological role of ferritin expression in skin cells. The investigation consisted of measurements of serum peroxide levels, serum total antioxidative potential levels and immunohistochemical analyses of ferritin in skin tissue samples. Serum peroxide levels were significantly higher and serum total antioxidative potential levels were significantly lower in rosacea patients than in healthy controls (p<0.05). Compared to controls, the number of ferritin positive cells was significantly higher (p<0.001) in skin samples of patients with rosacea. The presence of ferritin was significantly higher in patients with severe stage of disease (p<0.001). The statistically significant differences in the expression of ferritin, the higher peroxide levels and lower antioxidative potential support the onset of systemic oxidative stress in rosacea patients.
Projekt / tema: 098-0982464-2519
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti,Kliničke medicinske znanosti
Broj citata:
Altmetric:
DOI: 10.1016/j.jaad.2008.10.014
URL cjelovitog teksta:
Google Scholar: Oxidative stress and ferritin expression in the skin of rosacea patients
Upisao u CROSBI: marija@irb.hr (marija@irb.hr), 6. Vel. 2009. u 13:55 sati



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