engleski

The number of neurons of the human hippocampal formation in normal aging and Alzheimer's disease

Compared with age-matched controls, a significant reduction of subicular neurons represent a most profound and a most detrimental deficit in AD patients, because fibers of subicular neurons constitute the 'back projections' necessary for establishing declarative long-term memories and serve as a major efferent component of the hippocampal formation.

cortex ; memory ; stereology ; neurobiology

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