crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 385810

Časopis

Autori: Banić, Marko; Sutlić, Željko; Biočina, Bojan; Kujundžić, Milan; Fabijanić, Damir; Ljubičić, Neven; Pleško, Sanja; Buljevac, Mladen; Kardum, Duško; Čabrijan, Željko; Grgurević, Ivica; Urek, Marija; Tadić, Mario; Hulak, Vanja; Petrovečki, Mladen; Bedenikovič, V.; Starčević, Boris; Rotkvić, Ivo
Naslov: Peptic ulcer disease in dyspeptic patients with ischemic heart disease: search and treat?
( Peptic ulcer disease in dyspeptic patients with ischemic heart disease: search and treat? )
Izvornik: Zeitschrift fur Gastroenterologie (0044-2771) 43 (2005), 6; 581-586
Vrsta rada: članak
Ključne riječi: peptic ulcer disease; ischemic heart disease; Helicobacter pylori; dyspepsia; NSAIDs; aspirin
( peptic ulcer disease; ischemic heart disease; Helicobacter pylori; dyspepsia; NSAIDs; aspirin )
Sažetak:
Objective: The aim of this study was to determine the prevalence and risk factors for peptic ulcer disease (PUD) in dyspeptic patients with ischemic heart disease (IHD), and to assess whether the healing of PUD before coronary artery bypass grafting (CABG) could reduce the need for urgent postoperative endoscopy. Patients and Methods: A series of 894 patients referred to Dubrava University Hospital in Zagreb for elective CABG during the period from May 1998 until April 2001 was prospectively analysed. Dyspepsia was assessed by a questionnaire, PUD by upper gastrointestinal endoscopy, and H. pylori status by histology/Giemsa staining and the rapid urease test. The need for urgent postoperative endoscopy (hematemesis and/or melena, sudden onset of anemia or unexplained epigastric pain) was compared between the prospective study group of 894 patients and a series of 463 patients referred for CABG to Dubrava University Hospital during the period from January 1997 until April 1998. Results: Gastroduodenal dyspepsia predominated in 184 (20.6 %) patients, 142 (77.2 %) of them with Helicobacter (H.) pylori infection and 69 (37.5 %) with verified PUD. Univariate analysis indicated the increased risk of multiple PUD to be related to a previous diagnosis of PUD (OR 3.61, 95 % CI 1.32 - 9.82), H. pylori infection (OR 18.86, 95 % CI 2.31 - 153.98), use of aspirin (OR 5.70 ; 95 % CI 1.80 - 18.03) and left coronary artery occlusions (3.10, 95 % CI 1.00 - 9.59). Multivariate analysis pointed to H. pylori infection (OR 16.30, 95 % CI 1.57 - 168.53) and left coronary artery occlusions (OR 4.84, 95 % CI 1.05 - 22.30) as independent risk factors for multiple PUD. The OR for urgent postoperative endoscopy due to a major gastrointestinal event was 9.9 (95 % CI 2.2 - 45.1) and the OR for active peptic ulcer with stigmata of recent bleeding was 6.9 (95 % CI 1.4 - 33.1) in the group of patients with IHD who were not submitted to evaluation for dyspepsia prior to elective heart surgery. Conclusions: In areas with a high prevalence of H. pylori infection, endoscopy and a “ search and treat” strategy for IHD patients with dyspepsia before elective cardiac surgery should significantly reduce the need for urgent postoperative endoscopy due to major gastrointestinal events.
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Stručni
Znanstvena područja:
Kliničke medicinske znanosti
URL cjelovitog teksta:
Google Scholar: Peptic ulcer disease in dyspeptic patients with ischemic heart disease: search and treat?
Upisao u CROSBI: bksenija@medri.hr (bksenija@medri.hr), 16. Ožu. 2009. u 14:12 sati



  Verzija za printanje   za tiskati


upomoc
foot_4