engleski

Possible discrepancies between dicentric chromosome frequencies and recorded ionizing radiation doses: in vivo study

Beckground: The available data on the effects of radiation on humans are limited to the reports of accidental exposure or studies of patients under diagnostic and therapeutic treatment; few reports refer to a occupationally exposed population groups. Methods: The research was conducted on 66 subjects employed in the Department of Nuclear Medicine and 41 nonemployed controls. For each of them chromosomal analysis and gamma-spectrometer analysis of 24-hour urine were carried out. Exposure doses were measured usung film-badge dosimetry. Results: The comparison of dosimetric data obtained by film-badge measurements and the frequency of dicentric chromosomes in each subject revealed no correlation between the two observed parameters. Conclusions: In view of the above results, the subjects should be studied within job/task groups as they are far more likely to recieve comparable doses.

ionizong radiation; chromosome aberrations; internal contamination

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