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Pregled bibliografske jedinice broj: 402242

Časopis

Autori: Daraboš, Nikica; Hundrić-Hašpl, Željka; Hašpl, Miroslav; Markotić, Alemka; Daraboš, Anela; Moser, Carsten
Naslov: Correlation between synovial fluid and serum IL-1β levels after ACL surgery-preliminary report
( Correlation between synovial fluid and serum IL-1β levels after ACL surgery-preliminary report )
Izvornik: International orthopaedics (0341-2695) 33 (2009), 2; 413-418
Vrsta rada: članak
Ključne riječi: ACL surgery; synovial fluid and serum IL-1 ß
( ACL surgery; synovial fluid and serum IL-1 ß )
Sažetak:
The possibility of controlling the harmful intra-articular influence of elevated interleukin (IL)-1β synovial fluid concentration after anterior cruciate ligament (ACL) surgery could be useful. We investigated the correlation between serum and synovial fluid IL-1β levels following ACL reconstruction. We measured IL-1β concentration periodically in three synovial fluid and four serum samples in each of 20 patients receiving either autologous conditioned serum (ACS) containing endogenous anti-inflammatory cytokines including IL-1Ra and several growth factors (group A) or placebo (group B). A decrease in IL-1β synovial fluid concentration appeared to be more pronounced in absolute terms in group A. In eight patients serum IL-1β was detected on the 6th postoperative day. In four of them whose synovial fluid levels were over 10 pg/ml on the 6th postoperative day, serum IL-1β was detected on the 10th postoperative day. The results were different in group B. Correlation between serum and synovial fluid IL-1β appearance persists in patients after ACL surgery and ACS application. This study is an example of ACS influence on the ACL healing process controlling the IL-1β levels on the basis of the serum IL-1β detection.
Projekt / tema: 108-1080327-0161, 143-1430115-0103
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
URL Internet adrese: http://link.springer.com/article/10.1007%2Fs00264-008-0649-1
http://commerce.metapress.com/content/q224p160k54h5414/resource-secured/?target=fulltext.pdf&sid=iyl12345t0w0cpqq1yvtkz20&sh=www.springerlink.com
http://link.springer.com/article/10.1007%2Fs00264-008-0649-1
Broj citata:
Altmetric:
DOI: 10.1007/s00264-008-0649-1
URL cjelovitog teksta: http://link.springer.com/article/10.1007%2Fs00264-008-0649-1
Google Scholar: Correlation between synovial fluid and serum IL-1β levels after ACL surgery-preliminary report
Upisao u CROSBI: mhaspl@mef.hr (mhaspl@mef.hr), 4. Lip. 2009. u 14:21 sati
Napomene:
Rad je kao poster prezentiran na skupu Combined SICOT/RCOST 2009 Annual Meeting, održanom od 29.10.-01.11.2009., Pattaya, Tajland



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