crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 407982

Časopis

Autori: Markotić, Alemka; Škerk, Višnja; Cvetko Krajinović, Lidija; Beus, Antun
Naslov: Is the clinical picture of Schnitzler syndrome always Schnitzler syndrome?
( Is the clinical picture of Schnitzler syndrome always Schnitzler syndrome? )
Izvornik: Clinical and experimental rheumatology (0392-856X) 27 (2009), 3; 507-509
Vrsta rada: prikaz
Ključne riječi: Schnitzler syndrome; interleukine (IL)-1; granulocytecolony stimulating factor (G-CSF); IL-32 alpha; IL-17E (IL-25); NK-cells; CD40L (CD154)
( Schnitzler syndrome; interleukine (IL)-1; granulocytecolony stimulating factor (G-CSF); IL-32 alpha; IL-17E (IL-25); NK-cells; CD40L (CD154) )
Sažetak:
Here we present two cases, a female and a male patient with Schnitzler-like syndrome. Both patients had two major (monoclonal gammopathy and chronic urticaria) and almost all minor symptoms (e.g. arthralgia, bone pain, fever, etc.) of Schnitzler syndrome. It is considered that interleukine (IL)-1 has important influence on immunopathogenesis of Schnitzler syndrome. However, when looked at the immune response in our two patients, we found significant differences between them. In the sera of th efemale patient, IL-1beta was increased. However, the highest increase was found for granulocyte-colony stimulating factor (G-CSF), IL-32 alpha and IL-17E (IL-25). Th emale patient had a significant increase in th epercentage of NK-cells, a decrease in CD4+ helper cells and no increase in cytokine levels. In both patients an increase in CD40L (CD154) was found. Our statement is that, besides clinical symptoms and signs, additional immune parameters should be tested before diagnosis of Schnitzler syndrome is established.
Projekt / tema: 143-1430115-0103, 143-1080002-0050, 108-0000000-3489
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
URL Internet adrese: http://www.ncbi.nlm.nih.gov/pubmed/19604447
URL cjelovitog teksta:
Google Scholar: Is the clinical picture of Schnitzler syndrome always Schnitzler syndrome?
Upisao u CROSBI: apavelic@bfm.hr (apavelic@bfm.hr), 8. Lip. 2009. u 16:12 sati



  Verzija za printanje   za tiskati


upomoc
foot_4