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Pregled bibliografske jedinice broj: 430314

Časopis

Autori: Titlić, Marina; Jukić, Ivana; Tonkić, Ante; Buča, Ante; Aleksić-Shihabi, Anka
Naslov: Lamotrigine therapy for resistant pain in radicular lesions of cervical segments C4-C5 and C5-C6: a case report
( Lamotrigine therapy for resistant pain in radicular lesions of cervical segments C4-C5 and C5-C6: a case report )
Izvornik: Acta clinica Croatica (0353-9466) 48 (2009), 2; 157-160
Vrsta rada: Case report
Ključne riječi: spinal cord disease; therapy; neuralgia physiopathology; neuralgia; drug therapy; anticonvulsants; pharmacology; pain; drug therapy
( spinal cord disease; therapy; neuralgia physiopathology; neuralgia; drug therapy; anticonvulsants; pharmacology; pain; drug therapy )
Sažetak:
Radicular pain syndromes caused b< disk herniation are often accompanied b< incomplete cental cord syndrome. Intensiv epain is difficult to control with standard analgesics. Antiepileptics of new generation have shown significant efficacy in treating pain syndromes, trigeminal neuralgia, diabetic neuropathy, migraines, etc. The treatment of radicular pain with lamotrigine, a new generation antiepileptic, turned out to be effective in lumbar disk radicular conflicts, justigying its application for resistant pain in cervical segment. In our patient, pain intensity was signficantly reduced with gradual titration of lamotrigine to a dose of 200 mg/da<. Pain intensity measurd by the visual analog scale significantly decreased from 100 to 20 mm during eight weeks of titration. The blood concentration of the drug measured b< the method of high performance liquid chromatography was 13.65 umol/l. The patients quality of life improved greatly. It is necessary to further evaluate the efficacy of lamotrigine in the treatment of resistant radicular damage.
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
URL Internet adrese: http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=64177
URL cjelovitog teksta:
Google Scholar: Lamotrigine therapy for resistant pain in radicular lesions of cervical segments C4-C5 and C5-C6: a case report
Upisao u CROSBI: mtitlic@mefst.hr (mtitlic@mefst.hr), 13. Lis. 2009. u 22:36 sati



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