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Pregled bibliografske jedinice broj: 433405

Zbornik radova

Autori: Žarković, Neven; Čipak Gasparović, Ana; Cindrić, Marina; Waeg, Georg; Borović Šunjić, Suzana; Mrakovčić, Lidija; Jaganjac, Morana; Kolenc, Danijela; Andrišić, Luka; Gverić Ahmetašević, Snježana; Katušić, Ana; Cherkas, Andriy; Jurić Sekhar, Gordana; Wildburger, Renate; Žarković, Kamelija
Naslov: 4-Hydroxynonenal-protein adducts as biomarkers of oxidative stress, lipid peroxidation and oxidative homeostasis
Izvornik: Free Radicals Health and Lifestyle : contributions from the Europe Meeting of the Society for Free Radical Research / Caporossi, Daniela ; Pigozzi, Fabio ; Sabatini Stefania (ur.). - Rim : Medimond International Proceedings , 2009. 37-44 (ISBN: 978-88-7587-515-2).
Skup: Free Radicals Health and Lifestyle
Mjesto i datum: Rim, Italija, 26.-29.08.2009.
Ključne riječi: 4-hydroxynonenal; lipid peroxidation; oxidative stress; oxidative homeostasis
Sažetak:
Lipid peroxidation and its end products reactive aldehydes are implicated in pathogenesis of various diseases such as cardiovascular diseases, neurodegenerative diseases, diabetes mellitus and cancer. 4-hydroxy-2-nonenal (HNE) is the most intriguing one due to its involvement in various (patho)physiological processes. The concept of HNE as toxic messenger of free radicals evolved further into the concept of HNE as biomarker, growth regulating factor and signalling molecule. That allowed consideration of oxidative stress also as physiological process introducing new term ”oxidative homeostasis”, which implies involvements of reactive oxygen species (ROS) and lipid peroxidation in various physiological processes. According to such concept of oxidative homeostasis, the HNE-protein adducts should be present not only under pathological but also under physiological circumstances in various human and animal tissues, as revealed in this article showing briefly results of several genuine immunohistochemical studies.
Vrsta sudjelovanja: Predavanje
Vrsta prezentacije u zborniku: Cjeloviti rad (više od 1500 riječi)
Vrsta recenzije: Međunarodna recenzija
Projekt / tema: 098-0982464-2519, 108-0000000-0028
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
Upisao u CROSBI: mstroser@mef.hr (mstroser@mef.hr), 10. Stu. 2009. u 15:25 sati



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