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Pregled bibliografske jedinice broj: 444027

Zbornik radova

Autori: Šaban, Nina; Vučinić, Srđan; Zorc, Branka; Perković, Ivana; Butula, Ivan; Mintas, Mladen; Kraljević Pavelić, Sandra
Naslov: Biological effects of two new amino-acid hydroxyurea derivatives on SW620 cell line in vitro
( Biological effects of two new amino-acid hydroxyurea derivatives on SW620 cell line in vitro )
Izvornik:
Skup: Kongres Hrvatskog društva za biokemiju i molekularnu biologiju – HDBMB2008
Mjesto i datum: Osijek, Hrvatska, 17.-20.09.2008.
Ključne riječi: hydroxyurea derivatives; proteomics; antitumor effect
( hydroxyurea derivatives; proteomics; antitumor effect )
Sažetak:
Colon cancer is the third most common cancer in men and the second most common cancer in women. Risk factors include age, a diet rich in fat and cholesterol, inflammatory bowel disease (especially ulcerative colitis), and genetic predisposition, including hereditary polyposis and nonpolyposis syndromes. If detected early, colon cancer is curable by surgery. Adjuvant chemotherapy can prolong survival in disease that has reached the lymph nodes. We studied the effects of two previously screened amino-acid hydroxyurea derivatives (compounds A and B) on the cell cycle and apoptosis of colon cancer cell line SW620, which is derived from metastatic site of the lymph node from the patient with colon cancer. We used the methods of cell cycle analysis, annexin test, western blotting and two-dimensional gel electrophoresis.
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Nije objavljen
Vrsta recenzije: Nema recenziju
Projekt / tema: 098-0982464-2393
Izvorni jezik: eng
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
Upisao u CROSBI: sandrakp@uniri.hr (sandrakp@uniri.hr), 11. Vel. 2010. u 21:53 sati



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