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Pregled bibliografske jedinice broj: 450980

Časopis

Autori: Mrakovčić, Lidija; Cindrić, Marina; Žarković, Neven; Borović Šunjic, Suzana; Moguš Milanković, Andrea; Wildburger, Renate
Naslov: In vitro model of bone regeneration with bioactive glass and lipid peroxidation
Izvornik: Clinical and Experimental Medical Journal (2060-6249) 4 (2010), 1; 73-78
Vrsta rada: članak
Ključne riječi: bone regeneration ; bioactive glass ; 4-hydroxynonenal
Sažetak:
Tissue regeneration is complex biological process of vital importance since it allows renewal of damaged cells and organs. Healing of long bones and large joints is often extended or incomplete primarily in elderly people or in polytraumatized patients. Various attempts are done to solve this severe medical and social problem by development of novel bioactive materials, among which bioactive glass is the most attractive because of its osteoconductive and osteostimulative properties. Lipid peroxidation was defined as important parameter of systematic stress response in patients with traumatic brain injuries and bone fractures. The major bioactive marker and final product of lipid peroxidation, 4-hydroxynonenal (HNE) is particularly interesting biomolecule because it regulates differentiation, proliferation and apoptosis of cells and might therefore play important role regulating regeneration of damaged tissue such as bone. Therefore, in the present study we investigated the concept of using bioactive glass functionalised with HNE as an in vitro model of bone regeneration.
Projekt / tema: 098-0982929-2916, 108-0000000-0028, 098-0982464-2519
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Kemija,Temeljne medicinske znanosti
URL Internet adrese: http://akademiai.com/doi/abs/10.1556/CEMED.4.2010.1.7
Broj citata:
Altmetric:
DOI: 10.1556/CEMED.4.2010.1.7
URL cjelovitog teksta:
Google Scholar: In vitro model of bone regeneration with bioactive glass and lipid peroxidation
Upisao u CROSBI: mstroser@mef.hr (mstroser@mef.hr), 23. Ožu. 2010. u 15:39 sati



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