engleski

Increased sympathetic activity in coronary artery disease shifts centre frequency of heart rate variability spectra leftward

Long-term measured ratio between low and high frequency (LF/HF ratio) components of heart rate variability (HRV) spectra fails to describe autonomic effect in most of cardiac patients. It seems that an increase in sympathetic activity decreases frequency of autonomic oscillations and shifts the centre frequency of HRV spectra toward very low frequencies. To test that hypothesis, LF/HF ratio was compared with ratio between very low and low frequency (VLF/LF ratio) in 690 patients with coronary artery disease. Patients with lower overall HRV and weaker vagal activity had lower LF/HF ratio and higher VLF/LF ratio. As a rule, the lower the HRV, the higher the VLF/LF ratio and the lower LF/HF ratio (p< 0.01), thus proving that the increase in sympathetic activity shifts the centre frequency of spectral components leftward.

coronary artery disease; heart rate variability

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