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izvor podataka: crosbi

Gastroesophageal reflux and gastric hyperacidity in cystic fibrosis patients (CROSBI ID 161571)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Rožmanić, Vojko ; Tješić-Drinković, Dorian ; Banac, Srđan ; Ahel, Vladimir ; Tješić-Drinković, Duška ; Peršić, Mladen ; Votava-Raić, Ana Gastroesophageal reflux and gastric hyperacidity in cystic fibrosis patients // Paediatrics today (Tuzla), 6 (2010), 1; 45-52

Podaci o odgovornosti

Rožmanić, Vojko ; Tješić-Drinković, Dorian ; Banac, Srđan ; Ahel, Vladimir ; Tješić-Drinković, Duška ; Peršić, Mladen ; Votava-Raić, Ana

engleski

Gastroesophageal reflux and gastric hyperacidity in cystic fibrosis patients

Gastroesophageal reflux (GER) is increased in children with cystic fibrosis (CF). The role of gastric hyperacidity, which is common in CF patients with GER is not well characterized. Twenty-five CF children underwent 24 hour oesophageal pH monitoring. From each pH monitoring diurnal and nocturnal intervals were selected. In 10 patients 24-hour simultaneous oesophageal and gastric pH monitoring were performed.Thirteen of the 25 patients showed pathological GER. There were significantly more refluxes during diurnal pH monitoring. Nocturnal pH monitoring yielded significantly more refluxes longer than 5 minutes, longer episodes of refluxes and lower mean gastric and oesophageal pH. The method of choice for the diagnosis of gastroesophageal reflux in CF patients should be simultaneous oesophageal and gastric 24- hour monitoring including alert and sleep periods. Gastric acidity and reduced lung function facilitates reflux, which in turn might contribute to progression of pulmonary diseases as was seen in our patients

cystic fibrosis ; gastroesophageal reflux ; gastric hyperacidity ; children ; lung function ; pH monitoring

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Podaci o izdanju

6 (1)

2010.

45-52

objavljeno

1840-0914

1840-2968

Povezanost rada

Kliničke medicinske znanosti