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izvor podataka: crosbi

Chemistry and biochemistry of lipid peroxidation products (CROSBI ID 166766)

Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija

Guéraud, Françoise ; Atalay, Mustafa ; Bresgen, Nicolaus ; Čipak, Ana ; Eckl, Peter M. ; Huc, Laurence ; Jouanin, Isabelle ; Siems, Werner ; Uchida, Koji Chemistry and biochemistry of lipid peroxidation products // Free radical research, 44 (2010), 10; 1098-1124. doi: 10.3109/10715762.2010.498477

Podaci o odgovornosti

Guéraud, Françoise ; Atalay, Mustafa ; Bresgen, Nicolaus ; Čipak, Ana ; Eckl, Peter M. ; Huc, Laurence ; Jouanin, Isabelle ; Siems, Werner ; Uchida, Koji

engleski

Chemistry and biochemistry of lipid peroxidation products

Oxidative stress and resulting lipid peroxidation is involved in various and numerous pathological states including inflammation, atherosclerosis, neurodegenerative diseases and cancer. This review is focused on recent advances concerning the formation, metabolism and reactivity towards macromolecules of lipid peroxidation breakdown products, some of which being considered as ‘second messengers’ of oxidative stress. This review relates also new advances regarding apoptosis induction, survival/proliferation processes and autophagy regulated by 4-hydroxynonenal, a major product of omega-6 fatty acid peroxidation, in relationship with detoxication mechanisms. The use of these lipid peroxidation products as oxidative stress/lipid peroxidation biomarkers is also addressed.

lipid peroxidation; alkenals; 4-hydroxy-2-nonenal; glutathione; apoptosis; adducts; volatile aldehydes

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Podaci o izdanju

44 (10)

2010.

1098-1124

objavljeno

1071-5762

10.3109/10715762.2010.498477

Povezanost rada

nije evidentirano

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