Hrvatska znanstvena bibliografija (CROSBI)



Pregled bibliografske jedinice broj: 495072

Časopis

Autori: Alešković, Marija; Basarić, Nikola; Mlinarić-Majerski, Kata
Naslov: Optimization of the Suzuki coupling reaction in the synthesis of 2-[(2-substituted)phenyl]pyrrole derivatives
Izvornik: Journal of heterocyclic chemistry (0022-152X) 48 (2011), 6; 1329-1335
Vrsta rada: članak
Ključne riječi: synthesis of aminoarylpyrroles; Suzuki-Miyaura coupling; 2-(o-substituted aryl)pyrroles; Pd-catalyzed cross coupling
Sažetak:
A facile three-step synthesis of 2-(2-aminophenyl)pyrrole (1) and 2-(2- aminomethylphenyl)pyrrole (2) is reported by use of Suzuki coupling of N-Boc-pyrrol-2-yl boronic acid (3) and o-substituted aryl halogenides, followed by hydrogenation. The Pdcatalyzed cross coupling reaction is optimized to be applicable to a wide range of substitued aryl halogenides, with electron-donating and electron-withdrawing substituents, 5a-g. Moreover, Pdcatalyzed coupling of o-bromoaniline and 3 could be applied for the one step preparation of pyrrolo[1, 2-c]quinazolin-5(6H)-one (8). Keywords: Synthesis of aminoarylpyrroles, Suzuki-Miyaura coupling, 2-(o-substituted aryl)pyrroles, Pd-catalyzed cross coupling
Projekt / tema: 098-0982933-2911
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kemija
URL Internet adrese: http://onlinelibrary.wiley.com/doi/10.1002/jhet.792/abstract
Broj citata:
Altmetric:
DOI: 10.1002/jhet.792
URL cjelovitog teksta:
Google Scholar: Optimization of the Suzuki coupling reaction in the synthesis of 2-[(2-substituted)phenyl]pyrrole derivatives
Upisao u CROSBI: eluksa@irb.hr (eluksa@irb.hr), 15. Pro. 2010. u 10:44 sati