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Pregled bibliografske jedinice broj: 509918

Zbornik radova

Autori: Mihovilović, Karlo; Bacalja, Jasna; Galešić Ljubanović, Danica; Kovačević-Vojtušek, Ivana; Gracin, Sonja; Gustin, Denis; Vidas, Željko; Sabljar-Matovinović, Mirjana; Knotek, Mladen
Naslov: Impact of early steroid withdrawal (ESW) on progression of chronic biopsy scores after kidney transplantation
( Impact of early steroid withdrawal (ESW) on progression of chronic biopsy scores after kidney transplantation )
Izvornik: Nationa Kidney Foundation (NKF) 2011 Spring Clinical Meetings Abstracts ; u American journal of kidney diseases 57 (2011) (4) B1-B108
ISSN: 0272-6386
Skup: Nationa Kidney Foundation 2011 Spring Clinical Meetings
Mjesto i datum: Las Vegas, SAD, 26.04-01.05.2011.
Ključne riječi: early steroid withdrawal; chronic scores; kidney transplantation
( early steroid withdrawal; chronic scores; kidney transplantation )
Sažetak:
Long-term effects of ESW on development of chronic pathohistology changes in kidney allograft is unclear. In this study we compared chronic scores on protocol biopsies in Caucasian kidney recipients(N=41) without DGF with ESW vs. continuous steroids on top of CNI and MMF. Induction consisted of IL-2RA or ATG. Protocol biopsies were done on day 0 and 1 year afer transplant. Chronic scores (ci, ct, cg, mm, cv and ah) were analyzed by Banff' 97 classification. ESW was not associated with changes in ci, ct, cg, mm and cv scores, but slight progression of ah score was noticed in ESW group(0.49±0.51 vs. 0.21±0.41 ; p=0.02). In multivariate analysis including recipient age and gender, donor age, type of donation (living or deceased) and type of transplant (kidney or kidney/pancreas), ESW was independently associated with progression of ah score (p=0.049). In conclusion, ESW may cause progression of ah score during first 12 months postransplant, without impact on other chronic scores.
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Nema recenziju
Projekt / tema: 044-0000000-3356
Izvorni jezik: eng
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
URL Internet adrese: http://www.sciencedirect.com/science/article/pii/S0272638611003696
Upisao u CROSBI: mknotek@mef.hr (mknotek@mef.hr), 11. Tra. 2011. u 18:18 sati
Napomene:
doi:10.1053/j.ajkd.2011.02.209



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