Impact of cigarette smoking on renal function in type 1 diabetes mellitus (CROSBI ID 572300)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Bulum, Tomislav ; Smirčić-Duvnjak, Lea ; Car, Nikica ; Prkačin Ingrid
engleski
Impact of cigarette smoking on renal function in type 1 diabetes mellitus
In this study of a large cohort of patients with type 1 diabetes we provided the evidence that cigarette smoking is associated with the development and progression of early diabetic renal damage (albuminuria). Cigarette smoking was more strongly related to albuminuria than with serum creatinine and creatinine clearance in our patients. It is possible that smoking could influence renal tubule and permeability functions independent of any specific effects on clinical propensity to nephropathy. Microalbuminuria is the earliest clinical indicator of diabetic nephropathy, and 25-80% of patients with type 1 diabetes and microalbuminuria go on progress to higher rates of urinary albumin excretion associated with progressive kidney disease. Cessation of smoking slow progression to renal failure, but the decision to stop smoking is difficult because of the high addictive potential of the habit. The challenge remains for diabetologists and nephrologists to motivate patients to stop smoking.
type 1 diabetes; cigarette smoking; renal function
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Podaci o prilogu
2011.
objavljeno
Podaci o matičnoj publikaciji
World Congress of Nephrology Book of Abstracts, 2011. SA180
Podaci o skupu
World Congress of Nephrology
poster
08.04.2011-12.04.2011
Vancouver, Kanada