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Pregled bibliografske jedinice broj: 528849

Zbornik radova

Autori: Nigam, Vivek; Ban Kirigin, Tajana; Scedrov, Andre; Talcott, Carolyn; Kanovich, Max; Perovic, Ranko
Naslov: Towards an Automated Assistant for Clinical Investigations
Izvornik: ACM Digital Library / Luo, Gang ; Liu, Jiming ; Yang, Christopher C. (ur.). - ACM , 2012. 773-778 (ISBN: 978-1-4503-0781-9).
Skup: 2nd ACM SIGHIT International Health Informatics Symposium (IHI 2012).
Mjesto i datum: Miami, SAD, 28-30.01.2012.
Ključne riječi: Formal Methods; Timed Collaborative Systems; Clinical Investigations
Before a drug can be made available to the general public, its ef- fectiveness has to be experimentally evaluated. Experiments that in- volve human subjects are called Clinical Investigations (CIs). Since human subjects are involved, procedures for CIs are elaborated so that data required for validating the drug can be collected while ensuring the safety of subjects. Moreover, CIs are heavily regu- lated by public agencies, such as the Food and Drug Administra- tion (FDA). Violations of regulations or deviations from procedures should be avoided as they may incur heavy penalties and more im- portantly may compromise the health of subjects. However, CIs are prone to human error, since CIs are carried out by the study team, which might be overloaded with other tasks, such as hospital and/or pharmacy duties, other trials, etc. In order to avoid discrep- ancies, we propose developing an automated assistant for helping all the parties to correctly carry out CIs as well as to detect and prevent discrepancies as early as possible. This way the proposed automated assistant would minimize error, and therefore increase the safety of the involved subjects. This paper takes the first steps towards that direction. In particular, we propose a model for collab- orative systems with explicit time, called Timed Local State Transi- tion Systems (TLSTS), and argue that it can be used for specifying procedures and regulations for CIs, which mention time explicitly. Finally we show how to implement a TLSTS specification using Maude, an existing computational tool based on rewriting.
Vrsta sudjelovanja: Predavanje
Vrsta prezentacije u zborniku: Cjeloviti rad (više od 1500 riječi)
Vrsta recenzije: Međunarodna recenzija
Projekt / tema: 009-0091328-0941, 120-1203164-3074
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Puni text rada: 528849.ihi12.pdf (tekst priložen 24. Lis. 2013. u 23:57 sati)
Upisao u CROSBI: (, 5. Lis. 2011. u 13:45 sati

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