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Pregled bibliografske jedinice broj: 530131

Časopis

Autori: Krnić, Mladen; Modun, Darko; Budimir, Danijela; Gunjača, Grgo; Jajić, Ivan; Vuković, Jonatan; Salamunić, Ilza; Sutlović, Davorka; Kozina, Bernard; Boban, Mladen
Naslov: Comparison of acute effects of red wine, beer and vodka against hyperoxia-induced oxidative stress and increase in arterial stiffness in healthy humans
( Comparison of acute effects of red wine, beer and vodka against hyperoxia-induced oxidative stress and increase in arterial stiffness in healthy humans )
Izvornik: Atherosclerosis (Amsterdam) (0021-9150) 218 (2011), 2; 530-535
Vrsta rada: članak
Ključne riječi: Red wine; Hyperoxia; Oxidative stress; Arterial stiffness
( Red wine; Hyperoxia; Oxidative stress; Arterial stiffness )
Sažetak:
We determined and compared acute effects of different alcoholic beverages on oxygen-induced increase in oxidative stress plasma marker and arterial stiffness in healthy humans. Ten males randomly consumed one of four tested beverages: red wine (RW), vodka, beer (0.32 g ethanol/kg body wt) and water as control. Every beverage was consumed once, a week apart, in a cross-over design. The volunteers breathed 100% normobaric O2 between 60th and 90th min of 3 h study protocol. Plasma lipid peroxides (LOOH) and uric acid (UA) concentration, blood alcohol concentration (BAC) and arterial stiffness (indicated by augmentation index, AIx) were measured before and 30, 60, 90, 120 and 180 min after beverage consumption. Intake of all alcoholic beverages caused a similar increase of BAC. The oxygen-induced elevation in AIx was similarly reduced in all three groups relative to the control (3.4±1.3%, 5.4±2.2% and 0.2±1.6% vs. 13.7±2.6% for red wine, vodka, beer and control, respectively, 60 min after intake). Exposure to oxygen resulted in increased plasma LOOH in all groups. However, in RW group this increase was lowest (1.1±0.5) in comparison to the vodka (2.1±0.5), beer (1.6±0.3) and control (2.5±0.4M/L H2O2). 60 min after intake ofRWand beer plasmaUAsignificantly increased (34±4 and 15±3) in contrast to vodka and control (−6±2 and −8±2mol/L). All three alcoholic beverages provided similar protection against oxygen-induced increase in arterial stiffness, probably due to central vasodilatatory effect of alcohol itself, but only RW provided protection against oxygen-induced oxidative stress.
Projekt / tema: 216-2160547-0537
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti,Kliničke medicinske znanosti
URL Internet adrese: http://dx.doi.org/10.1016/j.atherosclerosis.2011.07.004
http://www.sciencedirect.com/science/article/pii/S0021915011005831
http://ac.els-cdn.com/S0021915011005831/1-s2.0-S0021915011005831-main.pdf?_tid=4c765ca99fb5fa34a60b458604d6b39a&acdnat=1338297258_745f8da8e78c242fcb6f682a9bc27cc7
Broj citata:
Altmetric:
DOI: 10.1016/j.atherosclerosis.2011.07.004
URL cjelovitog teksta: http://dx.doi.org/10.1016/j.atherosclerosis.2011.07.004
Google Scholar: Comparison of acute effects of red wine, beer and vodka against hyperoxia-induced oxidative stress and increase in arterial stiffness in healthy humans
Upisao u CROSBI: dbudimir@mefst.hr (dbudimir@mefst.hr), 13. Lis. 2011. u 10:37 sati



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