engleski

THERMOGRAPHIC VISUALISATION OF VASCULAR SIGNS IN PRE CANCEROUS BREAST LESIONS AND CARCINOMA

Thermography is a biologically inert diagnostic method which measures temperature differences across the skin surface using a highly sensitive infrared camera. In oncology, application of this method is based on one of the biological characteristics of carcinogenesis - the rise in metabolic activity of proliferating tumor which is accompanied by an increase in surrounding temperature. The visualization of “blood vessels” in thermograms is a consequence of need for abundant supply of nutritiens to maintain of the tumor growth. In order to do this, they increase circulation to their cells by sending out NO ( nitric oxide) to keep existing blood vessels open, recruit dormant vessels and create new ones ( neoangiogenesis). The purpose of this study is to show different pathological vascular thermographic signs in both, pre-cancerous and cancerous breast lesions. In this study we present 6 patients in which thermography was done prior to surgery and diagnosis was histopathologically confirmed. The visualization of “blood vessels” as pathologic thermographic sign is frequent and easy to recognize in breast thermograms, thus it play׳s an important role in early detection of breast lesions.

Thermographia; breast cancer; carcinogenesis; nitric oxide (NO);

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