crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 579096

Časopis

Autori: Jaganjac, Morana; Milković, Lidija; Čipak Gašparović, Ana; Mozetič, Miran; Recek, Nina; Žarković, Neven; Vesel, Alenka
Naslov: Cell adhesion on hydrophobic polymer surfaces
Izvornik: Materiali in Tehnologije (1580-2949) 46 (2012); 53-56
Vrsta rada: članak
Ključne riječi: plasma surface modification ; human osteosarcoma cells (HOS) ; biopolymers ; hydrophobic surface ; CF4 plasma
Sažetak:
Adhesion of human osteosarcoma (HOS) cells on hydrophobic polymer surface was studied. Surface of polymer polystyrene (PS) was made hydrophobic by treatment in plasma created in tetrafluoromethane gas (CF4). The PS samples were exposed for 30 s to CF4 plasma created by RF generator powered at 200 W. This treatment time allowed for optimal polymer surface functionalization with fluorine functional groups. This caused an increase of surface hydrophobicity from initial 85° to about 110° as measured by water contact angle. The HOS cells were deposited on untreated and plasma treated samples and incubated for 1, 2 and 6 days. Both untreated and plasma treated samples were tested for biocompatibility by two different methods: optical micrographs were used to study the cell morphology and MTT test was used to study the cell viability. The results showed better adhesion of cells on plasma treated samples with more hydrophobic surface in comparison to the untreated sample. MTT test revealed about 1.6-times higher activity of cell enzymes after 6-day incubation for plasma treated sample. Optical micrographs have shown that both untreated and fluorine-plasma treated polymer surfaces are not optimal for cell proliferation, since cells need about 2 days to adapt to the surface. After this adaptation time cells start to proliferate on the polymer surface, especially, on that one treated in plasma.
Projekt / tema: 098-0982464-2519
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL Internet adrese: http://mit.imt.si/Revija/izvodi/mit121/jaganjac.pdf
URL cjelovitog teksta:
Google Scholar: Cell adhesion on hydrophobic polymer surfaces
Upisao u CROSBI: mzivkovi@irb.hr (mzivkovi@irb.hr), 7. Svi. 2012. u 11:01 sati



  Verzija za printanje   za tiskati


upomoc
foot_4