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Pregled bibliografske jedinice broj: 58279

Časopis

Autori: Čolić, Miroslav; Pavelić, Krešimir
Naslov: Molecular mechanisms of anticancer activity of natural dietetic products
Izvornik: Journal of Molecular Medicine (0946-2716) 78 (2000); 333-336
Vrsta rada: članak
Ključne riječi: Dietetic supplements; Mechanism of anticancer activity
Sažetak:
The efficiency of dietetic supplements in cancer prevention and treatment is a popular and controversial subject of research. New in vitro and in vivo research results indicate that some dietetic supplements do indeed show anticancer activity. The strongest anticancer action has been demonstrated by natural compounds with multifunctional activity. For instance, antioxidants, which also bind to and modulate the activity of protein kinases involved in signal transduction cascades show both cytostatic and cytotoxic activity towards cancer cells. Other activities such as angiogenesis inhibition, nitric oxide synthase inhibition, and pro-oxidants production have also been observed. Catechins and polyphenols from plant extracts such as green tea show the strongest anticancer activity. The initial clinical trials with some flavonoid molecules are already underway.
Projekt / tema: 00981104
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL cjelovitog teksta:
Google Scholar: Molecular mechanisms of anticancer activity of natural dietetic products



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