Molecular mechanisms of anticancer activity of natural dietetic products (CROSBI ID 90455)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Čolić, Miroslav ; Pavelić, Krešimir
engleski
Molecular mechanisms of anticancer activity of natural dietetic products
The efficiency of dietetic supplements in cancer prevention and treatment is a popular and controversial subject of research. New in vitro and in vivo research results indicate that some dietetic supplements do indeed show anticancer activity. The strongest anticancer action has been demonstrated by natural compounds with multifunctional activity. For instance, antioxidants, which also bind to and modulate the activity of protein kinases involved in signal transduction cascades show both cytostatic and cytotoxic activity towards cancer cells. Other activities such as angiogenesis inhibition, nitric oxide synthase inhibition, and pro-oxidants production have also been observed. Catechins and polyphenols from plant extracts such as green tea show the strongest anticancer activity. The initial clinical trials with some flavonoid molecules are already underway.
Dietetic supplements; Mechanism of anticancer activity
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano