crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 630683

Zbornik radova

Autori: Bulum, Tomislav; Prkačin, Ingrid; Duvnjak, Lea
Naslov: Total and LDL cholesterol are associated with glomerular filtration rate in normoalbuminuric type 1 diabetic patients
Izvornik: Nephrology Dialysis Transplantation 2013 ; 28 (Suppl. 1): i167-i167.
ISSN: 0931-0509
Skup: 50th ERA-EDTA Congress
Mjesto i datum: Istanbul, Turska, 18-21.05.2013.
Ključne riječi: type 1 diabetes; serum lipids; renal function; glomerular filtration rate
Sažetak:
Studies have suggested a positive association between dyslipidemia and advanced chronic kidney disease, but the relation between these markers and normal or mild renal dysfunction has not been well investigated. The aim of this study was to investigate the associations of serum lipids, including total, LDL, HDL, HDL2, HDL3, VLDL cholesterol, and triglyceride levels with estimated glomerular filtration rate (eGFR) in normoalbuminuric type 1 diabetic patients. Study included 313 normoalbuminuric (UAE <30.0 mg/24h based on median UAE of at least two 24-h urine collections) type 1 diabetic patients with normal or mild decrease (eGFR > 60 mlmin-1 1.73 m2) renal function and before any interventions with statins, ACE inhibitors or angiotensin II receptor blockers. eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula. eGFR was significantly associated with total, LDL, HDL, HDL2, and HDL3 cholesterol (r=-0.21, -0.18, -0.17, -0.21, and -0.14, respectively, for all p<0.05). Stratifying serum lipids for degree of eGFR (60-90, >90 mlmin-1 1.73 m2) levels of total, LDL, HDL and HDL2 cholesterol were inversely related to eGFR, but trends were significant only for total (5.1 vs 4.6 mmol/L, p=0.02) and LDL cholesterol (2.9 vs 2.4 mmol/L, p=0.006). In this study we have shown that higher total and LDL cholesterol are associated with worsening of renal function normoalbuminuric type 1 diabetic patients. Prospective studies are needed to evaluate whether the observed lipid abnormalities play a role in the progression of renal function in type 1 diabetic patients.
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Međunarodna recenzija
Projekt / tema: 045-1080230-0516
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
Upisao u CROSBI: Tomislav Bulum (tbulum@idb.hr), 26. Svi. 2013. u 10:54 sati



Verzija za printanje   za tiskati


upomoc
foot_4