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Pregled bibliografske jedinice broj: 63393

Časopis

Autori: Škrablin, Snježana; Kalafatić, Držislav; Banović, Ivo; Kuvačić, Ivan; Juretić, Emilija; Goluža, Trpimir
Naslov: Antenatal predictors of the neurologic sequelae at 3 years of age: a multivariate analysis
( Antenatal predictors of the neurologic sequelae at 3 years of age: a multivariate analysis )
Izvornik: European Journal of Bostetrics & Gynecology and Reproductive Biology 92 (2000), 2; 173-180
Vrsta rada: članak
Ključne riječi: Doppler; fetal aorta; neurologic outcome
( Doppler; fetal aorta; neurologic outcome )
Sažetak:
Objective: To study the association between fetal blood flow abnormalities and the occurrence of long-term neurologic sequelae. Study design: Umbilical, aortic and middle cerebral artery blood flow parameters were obtained by Doppler examination and retrospectively analyzed in 128 high-risk singleton pregnancies, followed by neurologic examination of the surviving children at 3 years of age. Traditional parameters of neurologic outcome (Apgar scores, intrauterine growth retardation (IUGR), umbilical artery pH and base deficit, gestational age, birth weight, newborn encephalopathy, mode of delivery, fetal heart rate, neurosonographic examination) were included as possible confounding factors. Mann-Whitney U-test, Student's t-test, analysis of variance or Fisher's exact test, where applicable, were used for the univariate analysis. A stepwise logistic regression procedure was conducted to test the independent association of selected perinatal risk factors on neurological outcome. Statistical significance was assumed at P<0. 05. Results: Eighteen out of 114 surviving children suffered neurologic illness at 3 years of age. Four children had major neurologic dysfunction and the remaining 14 suffered minor or mild form of the disease. Although blood flow parameters and various perinatal parameters did not differ significantly between the group of children with major neurologic dysfunction and healthy children, aortic resistance index showed an independent association with occurrence of minor or mild neurologic disabilities. Conclusion: Antenatal evaluation of the aortic blood flow might be an important predictive variable for permanent neurologic disturbances.
Projekt / tema: 108032
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
SCI-EXP, SSCI i/ili A&HCI
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
URL cjelovitog teksta:
Google Scholar: Antenatal predictors of the neurologic sequelae at 3 years of age: a multivariate analysis



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