crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 650799

Časopis

Autori: Jaganjac, Morana; Vesel, Alenka; Milković, Lidija; Recek, Nina; Kolar, Metod; Žarković, Neven; Latiff, A.; Kleinschek, K.-S.; Mozetič, Miran
Naslov: Oxygen-rich coating promotes binding of proteins and endothelialization of polyethylene terephthalate polymers
Izvornik: Journal of biomedical materials research. Part A (1549-3296) 102 (2014), 7; 2305-2314
Vrsta rada: članak
Ključne riječi: endothelialization; plasma polymerization; reactive oxygen species; surface modification; vascular grafts
Sažetak:
The formation of endothelial cell monolayer on prosthetic implants has not sufficiently explored. The main reasons leading to the development of thrombosis and/or intimal hyperplasia is the lack of endothelialization. In the present work, we have studied the influence of oxygen and fluorine plasma treatment of polyethylene terephthalate (PET) polymers on human microvascular endothelial cell adhesion and proliferation. We characterized the polymer surface, wettability, and oxidation potential upon plasma treatment. Moreover, binding of serum and media compounds on PET surface was monitored by Quartz crystal microbalance method, X-ray photoelectron spectroscopy, and atomic force microscopy. Cell adhesion and morphology was assessed by light and scanning electron microscopy. The influence of plasma treatment on induction of cellular oxidative stress and cell proliferation was evaluated. The results obtained showed that treatment with oxygen plasma decreased the oxidation potential of the PET surface and revealed the highest affinity for binding of serum components. Accordingly, the cells reflected the best adhesion and morphological properties on oxygen-treated PET polymers. Moreover, treatment with oxygen plasma did not induce intracellular reactive oxygen species production while it stimulated endothelial cell proliferation by 25% suggesting the possible use of oxygen plasma treatment to enhance endothelialization of synthetic vascular grafts.
Projekt / tema: 098-0982464-2519
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
URL Internet adrese: Oxygen-rich coating promotes binding of proteins and endothelialization of polyethylene terephthalate polymers
Broj citata:
Altmetric:
DOI: 10.1002/jbm.a.34911
URL cjelovitog teksta:
Google Scholar: Oxygen-rich coating promotes binding of proteins and endothelialization of polyethylene terephthalate polymers
Upisao u CROSBI: Marina Cindrić (Marina.Cindric@irb.hr), 30. Lis. 2013. u 09:41 sati



  Verzija za printanje   za tiskati


upomoc
foot_4