In the period 1974-1989, 219 patients with supradiaphragmatic clinical stage I and II Hodkgin's disease were treated at the Institute of Oncology in Ljubljana ; Of these 95 (43%) patients underwent staging laparotomy. Of laparotomized patients, those with pathological stage III - IV, and of non-laparotomized, those with unfavorable prognostic factors (B-symptoms, bulky mediastinum) receive chemotherapy: the remaining patients were treated by irradiation. No statistically significant difference in the survival and disease-free surivival between laparotomized and non-laparotomized patients could be found. |