In vitro investigation of the antimicrobial activity of a series of lipophilic phenols and naphthols (CROSBI ID 225361)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Govender, Thavendran ; Govinden, Usha ; Mocktar, Chunderik ; Kruger, Hendrik G. ; Veljković, Jelena ; Cindro, Nikola ; Bobinac, Damir ; Žabčić, Ivana ; Mlinarić-Majerski, Kata ; Basarić, Nikola
engleski
In vitro investigation of the antimicrobial activity of a series of lipophilic phenols and naphthols
Five groups of phenols/naphthols (42 compounds in total) were synthesized and screened against Gram-positive Staphylococcus aureus and Bacillus subtilis, Gram-negative Escherichia coli and Klebsiella pneumoniae, and the fungus Candida albicans. Whereas compounds were found inactive against Gram-negative bacteria, potent activities against Gram-positive bacteria were observed. The activities correlate with the ability of molecules to form quinone methides, suggesting potential new modes of action.
Antimicrobial activity ; phenols ; naphthols ; quinone methides.
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Podaci o izdanju
69
2016.
44-50
objavljeno
0379-4350
1996-840X
10.17159/0379-4350/2016/v69a6