crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 816247

Časopis

Autori: Đevenica, Danka; Markotić, Anita; Režić-Mužinić, Nikolina; Jelaska, Igor; Zemunik, Tatijana; Delić, Hrvoje; Čikeš Čulić, Vedrana
Naslov: Hyperbaric environment upregulates CD15s expression on leukocytes, downregulates CD77 expression on renal cells and upregulates CD34 expression on pulmonary and cardiac cells in rat
Izvornik: Iranian Journal of Basic Medical Sciences (2008-3866) 19 (2016), 8; 821-828
Vrsta rada: članak
Ključne riječi: CD77 (globotriaosylceramide) ; CD15s (sialyl Lexis X antigen) ; hyperbaric environment ; CD34 antigen
Sažetak:
The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression. In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. Expression of CD11b and CD15s on leukocytes, as well as CD77 and CD34 expression on endothelial cells in cell suspensions of renal, pulmonary and cardiac tissue in rats after hyperbaric treatment and in control rats were determined by flow cytometry. Hyperbaric treatment significantly increased percentage of leukocytes expressing CD15s+CD11b- (from 1.71 ±1.11 to 23.42 ±2.85, P < 0.05). Hyperbaric treatment significantly decreased sum percentage of CD77+CD34- and CD77+CD34+ renal cells (from 16.35±5.5 to 4.48 ±1.28, P < 0.05). Hyperbaric treatment significantly increased percentage of CD34+ pulmonary cells (from 3.27±2.01 to 11.92 ±6.22, P < 0.05). Our study is the first reporting the hyperbaric environment influence on CD34+ heart cells in rats. The current findings of increased percentage of leukocytes expressing endothelial selectin ligand CD15s after hyperbaric treatment, point its role in endothelial damage prevention. We found out a significantly increase in percentage of CD34+ cardiac cells as well as CD34+ pulmonary cells in rats after HB treatment which could be a part of repair mechanism of injured endothelium caused by hyperoxia.
Projekt / tema: 216-2160133-0066
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
Puni text rada: 816247.IJBMS74621469993400.pdf (tekst priložen 18. Lis. 2016. u 16:31 sati)
URL Internet adrese: http://ijbms.mums.ac.ir/article_7462.html
Broj citata:
Altmetric:
DOI: 10.22038/ijbms.2016.7462
URL cjelovitog teksta:
Google Scholar: Hyperbaric environment upregulates CD15s expression on leukocytes, downregulates CD77 expression on renal cells and upregulates CD34 expression on pulmonary and cardiac cells in rat
Upisao u CROSBI: Vedrana Čikeš Ćulić (vedrana.cikes.culic@mefst.hr), 16. Svi. 2016. u 15:03 sati



  Verzija za printanje   za tiskati


upomoc
foot_4