engleski

Molecular, celular and medical aspects of the action of nutraceuticals and small molecules therapeutics: from chemoprevention to new drug development

Dietary supplements, functional foods and their concentrated, sometimes purified, active forms, the so-called nutraceuticals, are becoming increasingly popular everywhere. Small molecules that regulate signal transduction cascades and gene expression are tested by many pharmaceutical companies. A rapidly and exponentially growing industry (close to $30 billion in 1999 worldwide) exists to commercialise and exploit this interest. However, the scientific basis of action of such unproven products is in the very early stages of development. On the one hand, supporters claim "miracle cures." On the other hand, opponents argue that such unproven agents cause more damage than good.

nutriceutical; molecular mechanisms; chemoprevention

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