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 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 863112

Časopis

Autori: Allegri, Massimo; De Gregori, Manuela; Minella, Cristina E; Klersy, Catherine; Wang, Wei; Sim, Moira; Gieger, Christian; Manz, Judith; Pemberton, Iain K; MacDougall, Jane; Williams, Frances MK; Van Zundert, Jan; Buyse, Klaas; Lauc, Gordan; Gudelj, Ivan; Primorac, Dragan; Skelin, Andrea; Aulchenko, Yurii S; Lennart, C. Karssen; Kapural, Leonardo; Rauck, Richard; Fanelli, Guido
Naslov: ‘Omics’ biomarkers associated with chronic low back pain: protocol of a retrospective longitudinal study
Izvornik: BMJ Open (2044-6055) 6 (2016), 10; e012070-1-e012070-8
Vrsta rada: protocol
Ključne riječi: chronic low back pain (LBP), Omics biomarkers, retrospective study
Sažetak:
Chronic low back pain (CLBP) produces considerable direct costs as well as indirect burdens for society, industry and health systems. CLBP is characterised by heterogeneity, inclusion of several pain syndromes, different underlying molecular pathologies and interaction with psychosocial factors that leads to a range of clinical manifestations. There is still much to understand in the underlying pathological processes and the non-psychosocial factors which account for differences in outcomes. Biomarkers that may be objectively used for diagnosis and personalised, targeted and cost- effective treatment are still lacking. Therefore, any data that may be obtained at the ‘-omics’ level (glycomics, Activomics and genome-wide association studies—GWAS) may be helpful to use as dynamic biomarkers for elucidating CLBP pathogenesis and may ultimately provide prognostic information too. By means of a retrospective, observational, case-cohort, multicentre study, we aim to investigate new promising biomarkers potentially able to solve some of the issues related to CLBP
Projekt / tema: EK-FP7-602736
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
URL Internet adrese: http://bmjopen.bmj.com/content/6/10/e012070
http://dx.doi.org/10.1136/bmjopen-2016-012070
Broj citata:
Altmetric:
DOI: 10.1136/bmjopen-2016-012070
URL cjelovitog teksta:
Google Scholar: ‘Omics’ biomarkers associated with chronic low back pain: protocol of a retrospective longitudinal study
Upisao u CROSBI: Andrea Skelin (andreasv@agr.hr), 22. Vel. 2017. u 15:34 sati



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