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Pregled bibliografske jedinice broj: 868165

Ostalo

Autori: Frkanec, Leo
Naslov: Tripeptide hydrogelator (ffa) as a minimalist model of aggregation of a beta proteins
Izvornik: Systems Chemistry in Paris, École Normale Supérieure, Paris,
Vrsta: Predavanje
Godina: 2017
Ključne riječi: tripeptides, gels, Aβ-protein, β-sheet, amyloid dyes, biomaterial,
Sažetak:
Synthesis, characterization and self-assembly of small peptidic gelators based on amyloid β- protein. Morphology of prepared gels was investigated by Transmission Electron Microscopy (TEM). Organisation in gel assemblies at the molecular and the supramolecular level determined by using spectroscopic methods (NMR, FTIR, CD) pointed towards the β-sheet type of hydrogen bonding self-association of tripeptides in gel aggregates. Binding studies of tripeptide 6 with amyloid dyes, Congo Red and Thioflavin T (ThT) were carried out using fluorescence spectroscopy and confocal microscopy.
Projekt / tema: HRZZ-IP-2013-11-7387
Izvorni jezik: ENG
Znanstvena područja:
Kemija
Upisao u CROSBI: Leo Frkanec (Leo.Frkanec@irb.hr), 30. Ožu. 2017. u 12:04 sati
Napomene:
Predavanje se održalo 2.-3.2.2017.



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