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 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 949207

Časopis

Autori: Režić-Mužinić, Nikolina; Mastelić, Angela; Benzon, Benjamin; Markotić, Anita; Mudnić, Ivana; Grković, Ivica; Grga, Mia; Milat, Ana Marija; Ključević, Nikola; Boban, Mladen
Naslov: Expression of adhesion molecules on granulocytes and monocytes following myocardial infarction in rats drinking white wine
Izvornik: PLOS ONE (1932-6203) 13 (2018), 5;
Vrsta rada: članak
Ključne riječi: myocardial infarction, white wine, CD11b, CD44, neutrophils, monocytes
Sažetak:
Neutrophils and monocytes through their CD15s, CD11b and CD44 adhesion molecules are implicated in the initiation and resolution of cardiac inflammation as well as in healing processes after the myocardial infarction (MI). The aim of this study was to determine the effect of white wine consumption on granulocyte and monocyte CD15s, CD11b, and CD44 expression 24h after the surgically inflicted MI. Granulocytes and monocytes were analyzed by flow cytometry, using whole blood of male Sprague–Dawley rats that consumed white wine for 4 weeks. This group was compared with water only drinking controls, sham animals(subject to surgery without myocardial infarction) and baseline group (intact animals that received no intervention prior to being sacrificed). Sham animals did not differ from baseline animals in CD11b+CD44+ percentage and CD44+ median fluorescence intensity. Wine drinking was associated with striking increase in CD44 expression on monocyte subpopulations. Its expression was three and fourfold increased on monocytes and large monocytes, respectively, relative to the water only drinking controls. Because of known role of CD44 on suppression of post-infarction inflammation, its upregulation on granulocytes and monocytes may significantly contribute to the microenvironment favourable for the cardiac regeneration.
Projekt / tema: Croatian Science Foundation Project no. 8652
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kemija,Interdisciplinarne prirodne znanosti,Temeljne medicinske znanosti,Nutricionizam,Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)
URL Internet adrese: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196842
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945017/
Broj citata:
Altmetric:
DOI: 10.1371/journal.pone.0196842
URL cjelovitog teksta:
Časopis izlazi u samo elektroničkom izdanju: NE
Google Scholar: Expression of adhesion molecules on granulocytes and monocytes following myocardial infarction in rats drinking white wine
Upisao u CROSBI: Ana Marija Milat (ana.marija.milat@mefst.hr), 25. Srp. 2018. u 09:51 sati



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