Hrvatska znanstvena bibliografija (CROSBI)



Pregled bibliografske jedinice broj: 965822

Časopis

Autori: Škalamera, Đani; Matković, Marija; Uzelac, Lidija; Kralj, Marijeta; Mlinarić-Majerski, Kata; Bohne, Cornelia; Basarić, Nikola
Naslov: Photodeamination to quinone methides in cucurbit[n]urils: potential application in drug delivery
Izvornik: Organic & biomolecular chemistry (1477-0520) 16 (2018), 46; 8908-8912
Vrsta rada: članak
Ključne riječi: Drug delivery ; Cucurbit[n]uril ; Host-guest complexes ; Photochemistry ; Quinone methide ; Supramolecular chemistry ; Time-resolved spectroscopy
Sažetak:
We demonstrate a proof of principle for a new approach in the development of a drug delivery system. Positively charged prodrug (phenol) can form stable inclusion complex with CB[7], which enables more efficient delivery of the prodrug. After photochemical transformation (photoactivation) inside the complex, an active drug quinone methide (QM) is formed and released from the complex, since it is neutral molecule and forms less stable complex with CB[7].
Projekt / tema: HRZZ-IP-2014-09-6312, HRZZ-IP-2013-11-5660
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
Arts & Humanities Citation Index (A&HCI) (sastavni dio Web of Science Core Collectiona)
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kemija,Temeljne medicinske znanosti
URL Internet adrese: https://pubs.rsc.org/en/content/articlepdf/2014/OB/C8OB02605J?page=search
https://pubs.rsc.org/en/Content/ArticleLanding/2018/OB/C8OB02605J#!divAbstract
Broj citata:
Altmetric:
DOI: 10.1039/C8OB02605J
URL cjelovitog teksta:
Google Scholar: Photodeamination to quinone methides in cucurbit[n]urils: potential application in drug delivery
Upisao u CROSBI: Enidija Lukša (Enidija.Luksa@irb.hr), 6. Stu. 2018. u 11:19 sati