crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 458469

Časopis

Autori: Mrakovčić-Šutić, Ines; Bačić, Đordano; Golubović, Snježana; Bačić, Roberta; Marinović, Marin
Naslov: Cross-talk between NKT and regulatory T cells (Tregs) in modulation of immune response in patients with colorectal cancer following different pain management techniques
Izvornik: Collegium antropologicum (0350-6134) 35 (2011), S2; 57-60
Vrsta rada: članak
Ključne riječi: colorectal cancer; epidural analgesia; innate immunity; intravenous analgesia; NKT cells; regulatory T cells
Sažetak:
Natural killer T (NKT) and regulatory T cells (Tregs) play an important role in innate immune response. Natural killer (NK) and NKT cells are indispensable factors in the body’s ongoing defense against tumor development, as well as viral infection. NKT cells are a subset of T cells that shares properties of natural killer cells and conventional T cells. They are involved in innate immune responses, tumor rejection, post transplantation immunotherapy, immune surveillance and control of autoimmune diseases. They may also play both protective and harmful roles in the progression of certain autoimmune diseases, such as diabetes, lupus, atherosclerosis, and allergen-induced asthma. Immune surveillance involves the process whereby precancerous and malignant cells are recognized by the host immune system as damaged and are consequently targeted for elimination. The pharmacological management of postoperative pain in patients with malignancies uses very different techniques whose possible cytotoxic functions we still known very poor. The present study compared effects of two different postoperative pain management techniques in patients undergoing colorectal cancer surgery on the innate immunity. Our data indicate that the patients with colorectal cancer have significantly increased the percentage of Tregs and NKT cells. The values were statistically higher during epidural analgesia in comparison with intravenous analgesia, indicating that epidural pain management technique ameliorate the immune suppression after surgery.
Projekt / tema: 062-0620096-0092, 062-0620096-0094
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Social Science Citation Index (SSCI) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti,Kliničke medicinske znanosti
URL Internet adrese: http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=107505
URL cjelovitog teksta:
Google Scholar: Cross-talk between NKT and regulatory T cells (Tregs) in modulation of immune response in patients with colorectal cancer following different pain management techniques
Upisao u CROSBI: inesm@medri.hr (inesm@medri.hr), 1. Tra. 2010. u 10:57 sati
Napomene:
Rad je kao predavanje prezentiran na skupu 4. međunarodni kongres Hrvatskog društva "Albert Einstein", održanom 26.-28.05.2011., Rab, Hrvbatska ; uz domacu recenztiju objavljen u Knjizi sazetaka.



  Verzija za printanje   za tiskati


upomoc
foot_4