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Pregled bibliografske jedinice broj: 718817

Zbornik radova

Autori: Orlić, Lidija; Mikolašević, Ivana; Pavletić-Peršić, Martina; Đorđevic, Gordana; Anić, Kata; Devčić, Bosiljka; Rački, Sanjin
Naslov: WARFARIN-RELATED NEPHROPATHY – A CASE REPORT ON RENAL BIOPSY AND REVIEW OF THE LITERATURE
( WARFARIN-RELATED NEPHROPATHY – A CASE REPORT ON RENAL BIOPSY AND REVIEW OF THE LITERATURE )
Izvornik: Liječnički Vjesnik / Branimir Anić (ur.). - Zagreb :
ISSN: 0024-3477
Skup: 8.Hrvatski Internistički Kongres s međunarodnim sudjelovanjem
Mjesto i datum: Opatija, Hrvatska, 3.-5-listopada 2014.
Ključne riječi: Warfarin-related nephropathy; chronic kdiney disease; kidney biopsy
( Warfarin-related nephropathy; chronic kdiney disease; kidney biopsy )
Sažetak:
Patients with chronic kidney disease (CKD) are at increased risk of thromboembolic events. However, the use of anticoagulation in this population of patients remains a clinical challenge to the treating physician. This is mainly due to the fact that CKD patients have an increased risk of over-anticoagulation as they spend less time in the therapeutic range. Therefore, CKD patients require frequent dose adjustments and have higher bleeding risk. Warfarin-related nephropathy (WRN) is a recently introduced condition in patients with chronic kidney disease (CKD). WRN is clinically detected as an episode of unexplained acute kidney injury (AKI). It is defined as a serum creatinine (sCR) increase > 0.3 mg/dl (26, 5 µmol/L) within one week of an international normalized ratio (INR) measurement > 3.0 in a patient being treated with warfarin without clinical evidence of hemorrhage. Therefore, warfarin therapy can result in AKI by causing glomerular hemorrhage and renal tubular obstruction by red blood cell casts. WRN appears to accelerate the rate of progression of CKD and increase the risk of death in susceptible patients. We report on the renal biopsy of a patient on warfarin therapy with unexplained AKI and hematuria associated with increased INR. We would like to stress the necessity of an interdisciplinary approach to patients with warfarin therapy as well as many other conditions in order to prevent the consequences of this recently described entity.
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bazama podataka:
MEDLINE
Scopus
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Domaća recenzija
Izvorni jezik: eng
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti
Upisao u CROSBI: Sanjin Rački (sanjin.racki@uniri.hr), 5. Lis. 2014. u 18:47 sati



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